𝔖 Bobbio Scriptorium
✦   LIBER   ✦

L-lactate protects in vitro acetylcholinesterase (AChE) from inhibition by paraoxon (E 600)

✍ Scribed by Georg Petroianu; Ulrike Beha; Christina Roth; Wolfgang Bergler; Roderich Rüfer

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
445 KB
Volume
20
Category
Article
ISSN
0260-437X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

L-lactate reduces in vitro the inhibitio
L-lactate reduces in vitro the inhibition of butyrylcholinesterase (bche) by paraoxon (e 600)
✍ G. Petroianu; B. Kärcher; N. Kern; F. Hardt; U. Helfrich; R. Rüfer 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 278 KB

Intoxication with the organophosphorus compound paraoxon (POX), an inhibitor of serine hydrolases, is frequent. Oximes are the only enzyme reactivators clinically available. Serendipitous observation led us to the hypothesis that lactate might attenuate some of the POX effects. In vitro effects of l

Pralidoxime and l -lactate effects in vi
Pralidoxime and l -lactate effects in vitro on the inhibition of acetylcholinesterase by paraoxon: pralidoxime does not confer superior protection
✍ Georg Petroianu; Christina Roth; Ulrike Beha; Joseph Fisher; Wolfgang Bergler; R 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 143 KB

## Abstract Intoxication with the organophosphorus compound paraoxon (POX), an inhibitor of serine hydrolases, is frequent. Although oximes are the only enzyme reactivators presently available, clinical experience with their use was rather disappointing. Recent work has shown that under certain con

In vitro protection of red blood cell ac
In vitro protection of red blood cell acetylcholinesterase by metoclopramide from inhibition by organophosphates (paraoxon and mipafox)
✍ Georg Petroianu; Kholoud Arafat; Melita Kosanovic; Ayman Saleh; Vijayasarathy Ca 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 213 KB

Metoclopramide (MCP) is a dopamine receptor antagonist and serotonin receptor agonist widely used as an antiemetic and gastric prokinetic drug. In addition, MCP is a reversible inhibitor of cholinesterases from the human central nervous system and blood, and may have a red blood cell (RBC) acetylcho

In vitro protection of plasma cholineste
In vitro protection of plasma cholinesterases by metoclopramide from inhibition by paraoxon
✍ G. Petroianu; F. Kühn; C. Thyes; V. Ewald; A. Missler 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 107 KB

## Abstract Metoclopramide (MCP) is a dopamine receptor antagonist and serotonine receptor agonist widely used as an antiemetic and gastric prokinetic drug. In addition MCP is a reversible inhibitor of cholinesterases from human central nervous system and blood. MCP may have a cholinesterase protec