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JC Virus T-Antigen in Colorectal Cancer Is Associated with p53 Expression and Chromosomal Instability, Independent of CpG Island Methylator Phenotype

✍ Scribed by Nosho, Katsuhiko; Shima, Kaori; Kure, Shoko; Irahara, Natsumi; Baba, Yoshifumi; Chen, Li; Kirkner, Gregory J.; Fuchs, Charles S.; Ogino, Shuji


Book ID
122304042
Publisher
Neoplasia Press
Year
2009
Tongue
English
Weight
634 KB
Volume
11
Category
Article
ISSN
1522-8002

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## Abstract The CpG island methylator phenotype (CIMP) with widespread promoter CpG island methylation is a phenotype in colorectal cancer, associated with microsatellite instability (MSI) and __BRAF__ mutation. Genome‐wide hypomethylation may also play an important role in genomic instability. How