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Isolation and synthesis of 2″-N-formimidoylistamycins A and B, new istamycin components

✍ Scribed by Yukio Horiuchi; Daishiro Ikeda; Shuichi Gomi; Shinichi Kondo; Hamao Umezawa


Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
517 KB
Volume
109
Category
Article
ISSN
0008-6215

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✦ Synopsis


Two new istamycin components have been isolated from culture filtrates of Streptomyces tenjimariensis. Their structures were suggested to be 2"-N-formimidoylistamycins A and B by spectral analysis, and confirmed by synthesis starting from istamycins A, and BO, respectively. *Dedicated to Professor Sumio Umezawa on the occasion of his 73rd birthday and the 25th anniversary of the Microbial Chemistry Research Foundation. tTo whom correspondence should be addressed.


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