A new and facile synthesis of imidazo[2,1-b]oxazoles
✍ Scribed by Belew Mekonnen; George Crank; Donald Craig
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1997
- Tongue
- English
- Weight
- 967 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0022-152X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
An efficient and clean two step procedure for the synthesis of imidazo[2,1‐b]oxazoles has been developed from 2‐aminooxazoles using titanium(IV) chloride assisted cyclization, and a variety of imidazo[2,1‐b]oxazoles have been synthesized in good yields. The structure of one of the products was confirmed by X‐ray crystallographic analysis.
📜 SIMILAR VOLUMES
## Abstract 5‐Oxo‐5__H__‐[1,3]thiazolo[3,2‐__a__]pyrimidine‐6‐carboxylic acid (**4**), and 6‐methylimidazo[2,1‐__b__]thiazole‐5‐carboxylic acid (**17**) were reacted with amines **6a‐i** by the reaction with oxalyl chloride and __N, N__‐di methyl‐formamide as a catalyst into primary and secondary a