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Isolated Limb Perfusion With Melphalan and Tumor Necrosis Factor α for Advanced Melanoma and Soft-Tissue Sarcoma

✍ Scribed by Andrew J. Hayes; Susan J. Neuhaus; Matthew A. Clark; J. Meirion Thomas

Book ID
111771706
Publisher
Springer
Year
2006
Tongue
English
Weight
343 KB
Volume
14
Category
Article
ISSN
1068-9265

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Isolated limb perfusion with tumor necro
Isolated limb perfusion with tumor necrosis factor-α and melphalan for patients with unresectable soft tissue sarcoma of the extremities
✍ Eva M. Noorda; Bart C. Vrouenraets; Omgo E. Nieweg; Frits van Coevorden; Gooike 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB

## Abstract ## BACKGROUND Since 1992, isolated limb perfusion (ILP) with tumor necrosis factor‐α (TNFα) and melphalan has been used for the treatment of patients with unresectable soft tissue sarcomas of the extremities. The authors retrospectively studied the results of limb salvage surgery using

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Multifocal soft tissue sarcoma: Limb salvage following hyperthermic isolated limb perfusion with high-dose tumor necrosis factor and melphalan
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## Background and Objectives: The prognosis for recurrent multifocal limb soft tissue sarcoma (STS) is dismal due to systemic spread. However, many of these patients undergo amputation due to ineffective local control. The purpose of the present study was to determine whether isolated limb perfusi