## Background and Objectives: The prognosis for recurrent multifocal limb soft tissue sarcoma (STS) is dismal due to systemic spread. However, many of these patients undergo amputation due to ineffective local control. The purpose of the present study was to determine whether isolated limb perfusi
Outcome and prognostic factor analysis of 217 consecutive isolated limb perfusions with tumor necrosis factor-α and melphalan for limb-threatening soft tissue sarcoma
✍ Scribed by Dirk J. Grunhagen; Johannes H. W. de Wilt; Wilfried J. Graveland; Cornelis Verhoef; Albertus N. van Geel; Alexander M. M. Eggermont
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 176 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## BACKGROUND Since 1992, isolated limb perfusion (ILP) with tumor necrosis factor‐α (TNFα) and melphalan has been used for the treatment of patients with unresectable soft tissue sarcomas of the extremities. The authors retrospectively studied the results of limb salvage surgery using
## BACKGROUND. Recombinant tumor necrosis factor-a (rTNF-a) is
## Background: Isolated limb perfusion (ilp) with tumor necrosis factor alpha (tnf alpha) +/-interferon gamma (ifn gamma) and melphalan in patients with primarily irresectable soft tissue sarcoma is promising in terms of tumor regression and limb salvage. however, the feasibility of radiotherapy in