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Investigation for the leptin and LEP G2548A gene polymorphism in psoriasis


Book ID
116582843
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
57 KB
Volume
56
Category
Article
ISSN
1097-6787

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Functional analysis of the -2548G/A lept
✍ Marianna Terrasi; Elena Fiorio; Anna Mercanti; Mariusz Koda; Camilo A. Moncada; πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 French βš– 242 KB

## Abstract Leptin is overexpressed in human breast tumors and is produced by breast cancer cells in response to obesity‐related stimuli. The leptin promoter polymorphism Lep‐2548G/A can be associated with increased leptin secretion by adipocytes and elevated cancer risk. However, molecular mechani