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Association between the leptin gene 2548G/A polymorphism, the plasma leptin and the metabolic syndrome with psoriasis

✍ Scribed by Rania M. Abdel Hay; Laila A. Rashed

Book ID
111244891
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
221 KB
Volume
20
Category
Article
ISSN
0906-6705

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## Abstract Leptin is overexpressed in human breast tumors and is produced by breast cancer cells in response to obesity‐related stimuli. The leptin promoter polymorphism Lep‐2548G/A can be associated with increased leptin secretion by adipocytes and elevated cancer risk. However, molecular mechani