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2015 POSTER Functional analysis of the –2548G/ A leptin gene polymorphism in breast cancer cells

✍ Scribed by M. Terrasi; E. Fiorio; A. Russo; E. Surmacz


Book ID
118625619
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
83 KB
Volume
5
Category
Article
ISSN
1359-6349

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Functional analysis of the -2548G/A lept
✍ Marianna Terrasi; Elena Fiorio; Anna Mercanti; Mariusz Koda; Camilo A. Moncada; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 242 KB

## Abstract Leptin is overexpressed in human breast tumors and is produced by breast cancer cells in response to obesity‐related stimuli. The leptin promoter polymorphism Lep‐2548G/A can be associated with increased leptin secretion by adipocytes and elevated cancer risk. However, molecular mechani