A series of new ribonucleosides 1a-d having 4-oxoquinoline-3-carboxylic acid substituted with a chloro or bromo atom in the aromatic ring, as the nitrogen base, was synthesized and examined for anti-HIV activity. Compounds 1a and 1c showed a modest inhibition activity on HIV-1 reverse transcriptase,
✦ LIBER ✦
Investigating Carboxylic Acid Analogues of Ambruticin through Semi-Synthesis
✍ Scribed by Yuan Xu; Zhan Wang; Zong-Qiang Tian; Yong Li; Simon J. Shaw
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 83 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1860-7179
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