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ChemInform Abstract: Synthesis of Novel Nucleosides of 4-Oxoquinoline-3-carboxylic Acid Analogues.

✍ Scribed by Anderson D. da Matta; Carla Veronica B. dos Santos; Helena de S. Pereira; Izabel Christina de P. P. Frugulhetti; Mara Rita P. de Oliveira; Maria Cecilia B. V. de Souza; Nissin Moussatche; Vitor F. Ferreira

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
30
Category
Article
ISSN
0931-7597

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Synthesis of novel nucleosides of 4-oxoq
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A series of new ribonucleosides 1a-d having 4-oxoquinoline-3-carboxylic acid substituted with a chloro or bromo atom in the aromatic ring, as the nitrogen base, was synthesized and examined for anti-HIV activity. Compounds 1a and 1c showed a modest inhibition activity on HIV-1 reverse transcriptase,

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v