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Inverse editing of protons in two-dimensional homonuclear and heteronuclear relayed COSY spectra

✍ Scribed by U. Wollborn; D. Leibfritz

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
389 KB
Volume
29
Category
Article
ISSN
0749-1581

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✦ Synopsis

Abstract

Several 1D and 2D inverse proton editing pulse sequences have recently been introduced. One of these, the REPAY sequence, allows the individual editing of XH or XH~2~ groups. Some new 2D combinations of one‐ and two‐dimensional REPAY experiments with a COSY or TOCSY transfer are described. These combinations provide various possibilities for structural elucidation: the determination of heteronuclear long‐range coupling constants ^n^J(CH) (n = 2, 3), the editing of XH or XH~2~ groups in two‐dimensional H,H COSY spectra and the editing of XH or XH~2~ groups in X,H COSY spectra followed by a relayed transfer. In contrast to earlier versions of SHIPPED‐COSY experiments, the spectra show improved sensitivity and offer the possibility of selecting XH~2~ groups only, and contain no ^1^J(XH) coupling because of heteronuclear X decoupling.

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