✦ LIBER ✦
Two-dimensional spectra of intact tissue: Homonuclear Hartmann-Hahn spectroscopy provides increased sensitivity and information content as compared to COSY
✍ Scribed by Juli Alonso; Carles Arüs; William M. Westler; John L. Markley
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 493 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0740-3194
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Hartmann‐Hahn (HOH AHA) spectroscopy led to good definition of proton spin systems of metabolites such as lactate, (phospho) creatine, and carnosine from a 3‐g sample of excised frog gastrocnemius muscle in a 17‐min experiment. The sign of the HOHAHA cross‐peak intensity appears to provide additional information about interactions between metabolites and their protein binding sites. © 1990 Academic Press, Inc.