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Inv(11)(p15q22)/NUP98-DDX10 fusion and isoforms in a new case of de novo acute myeloid leukemia

✍ Scribed by Gorello, Paolo; Nofrini, Valeria; Brandimarte, Lucia; Pierini, Valentina; Crescenzi, Barbara; Nozza, Filomena; Daniele, Giulia; Storlazzi, Clelia Tiziana; Di Giacomo, Danika; Matteucci, Caterina; La Starza, Roberta; Mecucci, Cristina


Book ID
122810989
Publisher
Elsevier
Year
2013
Tongue
English
Weight
395 KB
Volume
206
Category
Article
ISSN
2210-7762

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## Abstract The __NUP98__ gene at 11p15 is known to be fused to __DDX10, HOXA9, HOXA11, HOXA13, HOXD11, HOXD13, LEDGF__, __NSD1, NSD3, PMX1__, __RAP1GDS1__, and __TOP1__ in various hematologic malignancies. The common theme in all __NUP98__ chimeras is a transcript consisting of the 5β€² part of __NU