## Abstract The __NUP98__ gene at 11p15 is known to be fused to __DDX10, HOXA9, HOXA11, HOXA13, HOXD11, HOXD13, LEDGF__, __NSD1, NSD3, PMX1__, __RAP1GDS1__, and __TOP1__ in various hematologic malignancies. The common theme in all __NUP98__ chimeras is a transcript consisting of the 5β² part of __NU
β¦ LIBER β¦
A new fusion gene NUP98-IQCG identified in an acute T-lymphoid/myeloid leukemia with a t(3;11)(q29q13;p15)del(3)(q29) translocation
β Scribed by Pan, Q; Zhu, Y-J; Gu, B-W; Cai, X; Bai, X-T; Yun, H-Y; Zhu, J; Chen, B; Weng, L; Chen, Z
- Book ID
- 110072977
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 503 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0950-9232
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The nucleoporin gene NUP98 has been reported to be fused to 9 partner genes in hematologic malignancies with 11p15 translocations. The NUP98-HOXA9 fusion gene has been identified in acute myeloid leukemia (AML) and chronic myelogenous leukemia with t(7;11)(p15;p15). We report here a novel NUP98 part