The objective of this study was to evaluate the interspecies scaling for therapeutic protein drugs to predict the systemic clearance in humans from animal data. This study was undertaken to examine whether the rule of exponents of Mahmood and Balian for the prediction of clearance of nonprotein drug
Interspecies scaling: prediction of human biliary clearance and comparison with QSPKR
โ Scribed by Marilyn E. Morris; Xinning Yang; Yash A. Gandhi; Suraj G. Bhansali; Lisa J. Benincosa
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 182 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0142-2782
- DOI
- 10.1002/bdd.1761
No coin nor oath required. For personal study only.
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