The objective of this study is to predict clearance of drugs in humans from animals which are excreted in the bile. Clearance (CL) of eight drugs known to be excreted in the bile were randomly selected from the literature. Scaling of CL was performed using at least three animal species. Using simple
Interspecies scaling of biliary excreted drugs: A comparison of several methods
โ Scribed by Iftekhar Mahmood
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 99 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0022-3549
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