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Interleukin-13-producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis

✍ Scribed by Fuschiotti, Patrizia; Larregina, Adriana T.; Ho, Johnan; Feghali-Bostwick, Carol; Medsger, Thomas A.


Book ID
118752712
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
566 KB
Volume
65
Category
Article
ISSN
0004-3591

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Effector CD8+ T cells in systemic sclero
✍ Patrizia Fuschiotti; Thomas A. Medsger Jr.; Penelope A. Morel πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 195 KB πŸ‘ 3 views

## Abstract ## Objective T lymphocytes play an important role in systemic sclerosis (SSc), a connective tissue disease characterized by inflammation, fibrosis, and vascular damage. While their precise role and antigen specificity are unclear, T cell–derived cytokines likely contribute to the induc