Enhanced production of interleukin-2 in patients with progressive systemic sclerosis. hyperactivity of cd4-positive t cells?
β Scribed by Hisanori Umehara; Shunichi Kumagai; Hiroshi Ishida; Toshihiko Suginoshita; Michiyuki Maeda; Hiroo Imura
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 665 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0004-3591
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## Objective: This study addresses the hypothesis that a profibrotic pattern of cytokines is produced in the lungs of patients with systemic sclerosis (ssc) and causes fibrosis. ## Methods: Using a reverse transcriptase-polymerase chain reaction technique, interleukin-4 (il-4), il-5, and interfer