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Interleukin 1 production by a human acute monocytic leukemia cell line (THP-1)

✍ Scribed by Steven B. Mizel; Barbara J. Andersen

Book ID
113132392
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
101 KB
Volume
70
Category
Article
ISSN
0008-8749

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Establishment and characterization of a
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## Abstract A human leukemic cell line (THP‐1) cultured from the blood of a boy with acute monocytic leukemia is described. This cell line had Fc and C3b receptors, but no surface or cytoplasmic immunoglobulins. HLA haplotypes of THP‐1 were HLA‐A2, ‐A9, ‐B5, ‐DRW1 and ‐DRW2. The monocytic nature of