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Interaction of cis-dichlorodiammineplatinum (II) with DNA

✍ Scribed by P. Horáček; J. Drobník


Book ID
115744648
Publisher
Elsevier Science
Year
1971
Weight
413 KB
Volume
254
Category
Article
ISSN
0005-2787

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Platinum determination in cis-dichlorodi
✍ Oldřich Vrána; Viktor Brabec 📂 Article 📅 1984 🏛 Elsevier Science 🌐 English ⚖ 684 KB

A simple polarogmphic assay for platinum determination in cis-dichlorodiammineplatinum(II)-DNA complexes is described. The method makes it possible to determine the free (unbound) drug in the presence of DNA or platinum-DNA complex, i.e., without a separation of free drug and macromolecular componen