Interaction of cis-diamminedichloroplatinum(II) with øX174 DNA
✍ Scribed by Zahoor, A; Lafleur, M V; Pluijmackers-Westmijze, E J; Edwards, D I
- Book ID
- 109835733
- Publisher
- Nature Publishing Group
- Year
- 1986
- Tongue
- English
- Weight
- 601 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0007-0920
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📜 SIMILAR VOLUMES
DNA samples isolated from control nuclei and nuclei treated by cis-and trans-diamminedichloroplatinum (DDP) were analyzed by gel electrophoresis. There were no changes in Mr when DNA isolated from nuclei treated with trans-DDP was analyzed. Scans of DNA isolated from nuclei treated with cis-DDP reve
## Abstract The interactions of the ribonucleotide poly C with __cis__‐ and __trans__‐diamminedichloroplatinum (II) were probed with Raman spectroscopy. Both platinum compounds attack the __N__‐1 position of the cytosine residue, while the __trans__ form appears to attack the PO~2~^−^ as well. Rama