Inactivation of α2-antiplasmin by limited reaction with cis-dichlorodiammineplatinum (II)
✍ Scribed by William A. Geary; Steven L. Gonias
- Book ID
- 113267246
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 966 KB
- Volume
- 994
- Category
- Article
- ISSN
- 0167-4838
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A clinically useful method is described for the quantitative analysis of platinum species derived from cis-dichlorodiammineplatinum(II) in urine. The drug and its biodegradation products are derivatized directly in urine by reaction with sodium diethyldithiocarbamate (DDTC) to form a common product,
AbstractÐOn treatment of N-tosylimines 1 and 4-hydroxyl-cis-butenyl arsonium salt 5 or sulfonium salt 11a with KOH in acetonitrile at room temperature, 2-(a-substituted N-tosylaminomethyl)-2,5-dihydrofurans 4 were obtained in moderate yields through a new ylide cyclization process. Ylide 2 acts form