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Integrin α5β1: a new purification strategy based on immobilized peptides

✍ Scribed by Wobbe, L. ;Zimmermann, D. ;Wißbrock, M. ;Urman, S. ;Sewald, K. ;Malešević, M. ;Sewald, N.

Book ID
111368274
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
160 KB
Volume
66
Category
Article
ISSN
1397-002X

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✍ Didier Boturyn; Pascal Dumy 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 105 KB

The cyclopeptide (-RGDfK-) is a potent and selective a V b 3 /a V b 5 integrin ligand. A methodology for the conjugation of cyclo(-RGDfK-) through the regioselective derivatisation of lysine side chains, either in solution or directly on the solid support, is described. This provides a rapid and fle