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Synthesis of a non-peptidic PET tracer designed for α 5β 1 integrin receptor

✍ Scribed by Monaco, Alessandra; Michelin, Olivier; Prior, John; Rüegg, Curzio; Scapozza, Leonardo; Seimbille, Yann

Book ID
121528124
Publisher
John Wiley and Sons
Year
2014
Tongue
French
Weight
384 KB
Volume
57
Category
Article
ISSN
0022-2135

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## Abstract The inhibition of integrin function is a major challenge in medicinal chemistry. Potent ligands are currently in different stages of clinical trials for the antiangiogenic therapy of cancer and age‐related macula degeneration (AMD). The subtype α5β1 has recently been drawn into the focu