Bone sialoprotein supports breast cancer
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V. Sung; J. T. Stubbs III; L. Fisher; A. D. Aaron; E. W. Thompson
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Article
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1998
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John Wiley and Sons
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English
⚖ 297 KB
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Bone sialoprotein (BSP), a secreted glycoprotein found in bone matrix, has been implicated in the formation of mammary microcalcifications and osteotropic metastasis of human breast cancer (HBC). BSP possesses an integrin-binding RGD (Arg-Gly-Asp) domain, which may promote interactions between HBC c