Integration and differentiation of neural stem cells after transplantation into the dysmyelinated central nervous system of adult mice
β Scribed by Marius Ader; Melitta Schachner; Udo Bartsch
- Book ID
- 109020579
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 261 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0953-816X
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Neural stem cells (NSCs) are the self-renewing, multipotent cells that generate neurons, astrocytes, and oligodendrocytes in the nervous system (Fig. 1a). Over the past decades, the confirmation that neurogenesis occurs in discrete areas of the adult brain and that NSCs reside in the adult brain has
## Abstract The human umbilical cord is a rich source of autologous stem and progenitor cells. Interestingly, subpopulations of these, particularly mesenchymalβlike cells from both cord blood and the cord stroma, exhibited a potential to be differentiated into neuronβlike cells in culture. Umbilica
in Sweden, where he has been active throughout his career. He initially trained as a neuroanatomist, and became interested in brain regeneration and repair in the early seventies. Together with his close collaborators Ulf Stenevi, Olle Lindvall, Fred Gage (now at the Salk institute in La Jolla, USA)