The factors inhibiting regeneration in the central nervous system (CNS) have been elaborated, debated, and studied for the past 70 years. Recent work has pointed to the fine balance that exists between repair and regeneration following CNS injury. Growth factors have featured prominently in this deb
Stem cell transplantation into the central nervous system and the control of differentiation
β Scribed by Hans S. Keirstead
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 50 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0360-4012
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
in Sweden, where he has been active throughout his career. He initially trained as a neuroanatomist, and became interested in brain regeneration and repair in the early seventies. Together with his close collaborators Ulf Stenevi, Olle Lindvall, Fred Gage (now at the Salk institute in La Jolla, USA)
Cell cultures enriched for oligodendrocyte precursors were prepared for male neonatal rat pups and transplanted into the spinal cord white matter of normal and x-irradiated syngeneic adult female rats. Transplanted cells were detected using a probe specific for the rat Y chromosome immediately after