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Integrated optical input grating couplers as biochemical sensors

โœ Scribed by Ph.M. Nellen; K. Tiefenthaler; W. Lukosz

Publisher
Elsevier Science
Year
1988
Weight
832 KB
Volume
15
Category
Article
ISSN
0250-6874

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๐Ÿ“œ SIMILAR VOLUMES

Model experiments with integrated optica
Model experiments with integrated optical input grating couplers as direct immunosensors
โœ Ph.M. Nellen; W. Lukosz ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 891 KB

Using an input grating coupler instrument and monomode optical waveguides, we studied the adsorption of various proteins (e.g. human immunoglobulins G and A (h-IgG and h-IgA), and avidin) on the waveguide surface. In model experiments for immunoassays, we also monitored as a function of time the for

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โœ W. Lukosz; Ph. M. Nellen; Ch. Stamm; P. Weiss ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 375 KB

We have demonstrated that output grating couplers on thin Si02-TiOz waveguides are sensors which respond (i) with sub-monomolecular sensitivity to the adsorption of molecules out of a gaseous or liquid sample covering the waveguide in the grating region, and (ii) to changes in the refractive index o