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Grating couplers as label-free biochemical waveguide sensors

โœ Scribed by K. Tiefenthaler


Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
336 KB
Volume
8
Category
Article
ISSN
0956-5663

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๐Ÿ“œ SIMILAR VOLUMES


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โœ W. Lukosz; Ph. M. Nellen; Ch. Stamm; P. Weiss ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 375 KB

We have demonstrated that output grating couplers on thin Si02-TiOz waveguides are sensors which respond (i) with sub-monomolecular sensitivity to the adsorption of molecules out of a gaseous or liquid sample covering the waveguide in the grating region, and (ii) to changes in the refractive index o

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We demonstrated the feasibility of using integrated optical output grating couplers in direct immunosensing. We monitored as functions of time, first the adsorption of an antigen (Ag) on the waveguide's surface, and subsequently, the binding of the corresponding antibody (Ab), i.e. the formation of