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Output grating couplers on planar waveguides as integrated optical chemical sensors

โœ Scribed by W. Lukosz; Ph. M. Nellen; Ch. Stamm; P. Weiss

Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
375 KB
Volume
1
Category
Article
ISSN
0925-4005

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โœฆ Synopsis

We have demonstrated that output grating couplers on thin Si02-TiOz waveguides are sensors which respond (i) with sub-monomolecular sensitivity to the adsorption of molecules out of a gaseous or liquid sample covering the waveguide in the grating region, and (ii) to changes in the refractive index of the sample. The effects (i) and (ii) induce changes in the effective refractive indices of the guided TE, and TM,, modes, to which the sensors respond with a change in direction of the outcoupled beams, which were measured with position-sensitive detectors having (sub)-millisecond response times. Waveguides coated with thin chemoresponsive adlayers are proposed as sensitive (bio)chemical sensors. Work on immunosensors or immunoassays is in progress.

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Output grating couplers on planar optical waveguides as direct immunosensors
โœ W. Lukosz; D. Clerc; Ph.M. Nellen; Ch. Stamm; P. Weiss ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 596 KB

We demonstrated the feasibility of using integrated optical output grating couplers in direct immunosensing. We monitored as functions of time, first the adsorption of an antigen (Ag) on the waveguide's surface, and subsequently, the binding of the corresponding antibody (Ab), i.e. the formation of