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Input and output grating couplers as integrated optical biosensors

โœ Scribed by W. Lukosz; D. Clerc; Ph.M. Nellen

Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
349 KB
Volume
25
Category
Article
ISSN
0924-4247

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๐Ÿ“œ SIMILAR VOLUMES

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Using an input grating coupler instrument and monomode optical waveguides, we studied the adsorption of various proteins (e.g. human immunoglobulins G and A (h-IgG and h-IgA), and avidin) on the waveguide surface. In model experiments for immunoassays, we also monitored as a function of time the for

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We have demonstrated that output grating couplers on thin Si02-TiOz waveguides are sensors which respond (i) with sub-monomolecular sensitivity to the adsorption of molecules out of a gaseous or liquid sample covering the waveguide in the grating region, and (ii) to changes in the refractive index o