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Integrase-defective lentiviral vectors: progress and applications

โœ Scribed by Banasik, M B; McCray, P B

Book ID
109855240
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
371 KB
Volume
17
Category
Article
ISSN
0969-7128

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## Abstract Lentiviral vectors efficiently integrate into the host genome of both dividing and nondividing cells, and so they have been used for stable transgene expression in biological and biomedical studies. However, recent studies have highlighted the risk of insertional mutagenesis and subsequ