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Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines

✍ Scribed by Donatella RM Negri, Alessandra Rossi, Maria Blasi, Zuleika Michelini, Pasqualina Leone, Maria Vincenza Chiantore, Silvia Baroncelli, Gemma Perretta, Andrea Cimarelli, Mary E Klotman, Andrea Cara

Book ID: 119908015
Publisher: BioMed Central
Year: 2012
Tongue: English
Weight: 482 KB
Volume: 9
Category: Article
ISSN: 1742-4690
DOI: 10.1186/1742-4690-9-69

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## Abstract ## Background Lentiviral vectors allow gene transfer into non‐dividing cells. Further development of these vector systems requires stable packaging cell lines that enable adequate safety testing. ## Methods To generate a packaging cell line for vectors based on simian immunodeficienc