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Development and use of SIV-based Integrase defective lentiviral vector for immunization

✍ Scribed by Zuleika Michelini; Donatella R.M. Negri; Silvia Baroncelli; Massimo Spada; Pasqualina Leone; Roberta Bona; Mary E. Klotman; Andrea Cara


Book ID
116961678
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
750 KB
Volume
27
Category
Article
ISSN
0264-410X

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## Abstract ## Background Lentiviral vectors allow gene transfer into non‐dividing cells. Further development of these vector systems requires stable packaging cell lines that enable adequate safety testing. ## Methods To generate a packaging cell line for vectors based on simian immunodeficienc