Inhibition of transplantable melanoma tumor development in mice by prophylactic administration of Ca-ascorbate
โ Scribed by Janos M. Varga; Luisa Airoldi
- Book ID
- 118942370
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 253 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0024-3205
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Melanoma-specific T-cells (CTLs) are specifically cytotoxic for autologous tumor, when assayed in vitro. To examine their effectiveness in vivo, we tested the ability of these human T-cells to inhibit growth of human melanoma xenografts by using a Winn assay. Nude mice receiving specific CTLs (n = 1
The growth rate of transplantable atlrenocortical tumors in male LAF I mice was fi)irnd to be inhibited in hypophysectomized and in adrenalectomized animals. Castration and sex hormones did not affect the growth of these tumors. /ti intact mice a striking inhibition of the growth rate of adrenocorti