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Inhibition of the apomorphine gnawing compulsion by amantadine

✍ Scribed by R. Hackman; P. Pentikäinen; P. J. Neuvonen; H. Vapaatalo

Book ID
112657240
Publisher
Springer
Year
1973
Tongue
English
Weight
349 KB
Volume
29
Category
Article
ISSN
1420-682X

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Influence of pheniramine and chlorphenir
Influence of pheniramine and chlorpheniramine on apomorphine induced compulsive gnawing in mice
✍ N. K. Dadkar; A. N. Dohadwalla; B. K. Bhattacharya 📂 Article 📅 1976 🏛 Springer 🌐 English ⚖ 401 KB

In mice, apomorphine (10 mg/kg s.c.) does not induce a compulsion to gnaw, but pretreatment with antihistamines, viz. pheniramine, chlorpheniramine and mepyramine, in doses ranging from 30 to 60 mg/kg i.p. caused gnawing activity. Mepyramine showed significantly less effect when compared to the othe