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Site of action of dopamine and apomorphine on compulsive gnawing behaviour in rats

✍ Scribed by A. M. Ernst; P. G. Smelik

Book ID
112646827
Publisher
Springer
Year
1966
Tongue
English
Weight
195 KB
Volume
22
Category
Article
ISSN
1420-682X

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In mice, apomorphine (10 mg/kg s.c.) does not induce a compulsion to gnaw, but pretreatment with antihistamines, viz. pheniramine, chlorpheniramine and mepyramine, in doses ranging from 30 to 60 mg/kg i.p. caused gnawing activity. Mepyramine showed significantly less effect when compared to the othe