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Inhibition of macrophage activation and phagocytosis by a novel NF-κB inhibitor, dehydroxymethylepoxyquinomicin

✍ Scribed by E. Suzuki; K. Umezawa


Book ID
116313762
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
630 KB
Volume
60
Category
Article
ISSN
0753-3322

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A new NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ), inhibited proliferation and induced apoptosis in human Burkitt lymphoma, HS-Sultan and Daudi cell lines. The activation of caspase-3 and the cleavage of caspase substrate PARP were observed after treatment with DHMEQ. The induction o