Targeting NF-κB and induction of apoptos
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Noriko Kimura; Yoshitaka Miyakawa; Kanoko Kohmura; Kazuo Umezawa; Yasuo Ikeda; M
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Article
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2007
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Elsevier Science
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English
⚖ 401 KB
A new NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ), inhibited proliferation and induced apoptosis in human Burkitt lymphoma, HS-Sultan and Daudi cell lines. The activation of caspase-3 and the cleavage of caspase substrate PARP were observed after treatment with DHMEQ. The induction o