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Induction of histidine decarboxylase in macrophages inhibited by the novel NF-κB inhibitor (−)-DHMEQ

✍ Scribed by Eriko Suzuki; Yoko Ninomiya; Kazuo Umezawa


Book ID
116297924
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
244 KB
Volume
379
Category
Article
ISSN
0006-291X

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A new NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ), inhibited proliferation and induced apoptosis in human Burkitt lymphoma, HS-Sultan and Daudi cell lines. The activation of caspase-3 and the cleavage of caspase substrate PARP were observed after treatment with DHMEQ. The induction o