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Inhibition of leukotriene B4in neutrophils by lipoxins A4and B4

✍ Scribed by P. Conti; M. Reale; R. C. Barbacane; M. R. Panara; M. Bongrazio


Publisher
SP Birkhäuser Verlag Basel
Year
1991
Tongue
English
Weight
205 KB
Volume
32
Category
Article
ISSN
1420-908X

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## Abstract Leukotrene (LT) B~4~ activates human polymorphonuclear neutrophils. (PMN) by binding to plasmalemmal receptors. It stimulates PMN to raise cytosolic calcium and degranulate. Both responses end within 15–30 sec. However, in < 15 sec, LTB~4~‐treated PMN lose the ability to respond further