Activation of human neutrophil LFA-1 (CD11a) by leukotriene B4
✍ Scribed by Richard S. Shames; Edward J. Goetzl
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 591 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0360-3997
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## Abstract Serum‐free culture of human monocytes in the presence of monoclonal antibodies to the LFA‐1 α chain (CD11a), CR3 α chain (CD11b) or β chain (CD18) bound to Sepharose induced the dose‐dependent production of cell‐associated interleukin (IL) 1 activity and of IL 1α and IL 1β antigens, but
Function of the LFA-1 and T4 molecules in the direct activation of resting human B lymphocytes by T lymphocytes\* Activated T lymphocytes can provide all of the signals necessary to induce the proliferation of resting B lymphocytes. The activation signal is presumably initiated through direct T-B ly