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Inhibition of indoleamine 2,3-dioxygenase ameliorates inflammation and fibrosis in experimental steatohepatitis

โœ Scribed by Vivoli, E.; Cappon, A.; Cozzi, A.; Navari, N.; Marra, F.


Book ID
123243422
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
54 KB
Volume
46
Category
Article
ISSN
1590-8658

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Indoleamine 2,3-dioxygenase in intestina
โœ Bobby J. Cherayil ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 119 KB

Indoleamine 2,3-dioxygenase (IDO) is a tryptophan catabolizing enzyme that has a number of immunoregulatory effects. It is expressed at high levels in the gastrointestinal tract, particularly in the small intestine, and has been implicated in the control of intestinal inflammation. However, its prec