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Inhibition of indoleamine 2, 3-dioxygenase-mediated tryptophan catabolism accelerates crescentic glomerulonephritis

✍ Scribed by Weiping Hou; Suzhi Li; Yinping Wu; Xiang Du; Fahuan Yuan

Book ID: 108701008
Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 435 KB
Volume: 156
Category: Article
ISSN: 0009-9104
DOI: 10.1111/j.1365-2249.2009.03902.x

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## Abstract ## Objective Indoleamine 2,3 dioxygenase (IDO) is a catabolic enzyme that initiates the kynurenine pathway of tryptophan degradation and has immunomodulatory properties. The aim of this study was to investigate the regulation of collagen‐induced arthritis by tryptophan catabolism media