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Inhibition of indoleamine 2,3-dioxygenase suppresses NK cell activity and accelerates tumor growth

โœ Scribed by Seiichiro Kai; Shigeru Goto; Kouichirou Tahara; Atsushi Sasaki; Katsunori Kawano; Seigo Kitano

Book ID
114752194
Publisher
Wiley (Blackwell Publishing)
Year
2003
Tongue
English
Weight
292 KB
Volume
3
Category
Article
ISSN
1533-869X

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โœ Maria Friberg; Ronald Jennings; Marwan Alsarraj; Sophie Dessureault; Alan Cantor ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 447 KB

The priming of an appropriate anti-tumor T cell response rarely results in the rejection of established tumors. The characteristics of tumors that allow them to evade a T cell-mediated rejection are unknown for many tumors. We report on evidence that the expression of the immunosuppressive enzyme, i