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Immunotherapeutic Suppression of Indoleamine 2,3-Dioxygenase and Tumor Growth with Ethyl Pyruvate

โœ Scribed by Muller, A. J.; DuHadaway, J. B.; Jaller, D.; Curtis, P.; Metz, R.; Prendergast, G. C.

Book ID
118241407
Publisher
American Association for Cancer Research
Year
2010
Tongue
English
Weight
339 KB
Volume
70
Category
Article
ISSN
0008-5472

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Innate and adaptive immunity play important roles in immunosurveillance and tumor destruction. However, increasing evidence suggests that tumor-infiltrating immune cells may have a dual function: inhibiting or promoting tumor growth and progression. Although regulatory T (Treg) cells induce immune t