Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice
✍ Scribed by Sándor Szántó, Tamás Koreny, Katalin Mikecz, Tibor T Glant…
- Book ID
- 120706481
- Publisher
- BioMed Central
- Year
- 2007
- Tongue
- English
- Weight
- 582 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1478-6354
- DOI
- 10.1186/ar2205
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📜 SIMILAR VOLUMES
## Abstract ## Objective Indoleamine 2,3 dioxygenase (IDO) is a catabolic enzyme that initiates the kynurenine pathway of tryptophan degradation and has immunomodulatory properties. The aim of this study was to investigate the regulation of collagen‐induced arthritis by tryptophan catabolism media
## Abstract ## Objective We have demonstrated previously that dendritic cells (DCs) modified with immunosuppressive cytokines, and exosomes derived from DCs can suppress the onset of murine collagen‐induced arthritis (CIA) and reduce the severity of established arthritis. Indoleamine 2,3‐dioxygena