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Inhibition of glutamine uptake regulates mTORC1, glutamine metabolism and cell growth in prostate cancer

โœ Scribed by Wang, Qian; Hardie, Rae-Anne; Balaban, Seher; Schreuder, Mark; Hoy, Andrew; van Geldermalsen, Michelle; Fazli, Ladan; Nagarajah, Rajini; Bailey, Charles; Rasko, John; Holst, Jeff

Book ID
125404855
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
93 KB
Volume
2
Category
Article
ISSN
2049-3002

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Notch is an ancient cell signaling system that regulates cell fate specification, stem cell maintenance and initiation of differentiation in many tissues. It has been reported that Jagged-1, a Notch ligand, is significantly over expressed in metastatic prostate cancer compared to localized prostate