Maturation of dendritic cells (DC), leading to migration and increased T cell stimulatory capacity, is essential for the initiation of immune responses. This process is triggered by a variety of stimuli, such as inflammatory cytokines, bacterial and viral products. Using a recombinant disabled infec
Inhibition of apoptosis by primary isolates of herpes simplex virus
β Scribed by K. R. Jerome; R. Fox; Z. Chen; P. Sarkar; L. Corey
- Book ID
- 106212896
- Publisher
- Springer Vienna
- Year
- 2001
- Tongue
- English
- Weight
- 166 KB
- Volume
- 146
- Category
- Article
- ISSN
- 1432-8798
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## Abstract The effects of highβspeed centrifugation on the isolation of herpes simplex virus (HSV) were studied. Aliquots of laboratory or clinical specimens were inoculated into test tubes and flatβbottomed tubes containing HEp2 monolayers. Test tubes were incubated at 35Β°C on roller drums (stand
ticularly dramatic reductions are seen in their neurovirulence. Furthermore, these viruses appear to be unable to reactivate from latent infections and therefore they would be unlikely to cause recurrent disease, and transmission would likely be reduced or eliminated. Resistance may also be acquire