Sensitivity of herpes simplex virus (HSV) isolates, from patients with recurrent infections, to human fibroblast ~3 interferon (IFN), was tested in vitro. Among 25 HSV strains, 12 were HSV-1, isolated from facial and labial lesions, and 13 were HSV-2 isolated from genital lesions. Viral sensitivity
Sensitivity monitoring of clinical isolates of herpes simplex virus to acyclovir
β Scribed by Dr. P. Collins; M. Nixon Ellis
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 727 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0146-6615
No coin nor oath required. For personal study only.
β¦ Synopsis
ticularly dramatic reductions are seen in their neurovirulence. Furthermore, these viruses appear to be unable to reactivate from latent infections and therefore they would be unlikely to cause recurrent disease, and transmission would likely be reduced or eliminated.
Resistance may also be acquired through more subtle mutations in the genes encoding TK or DNA poly-
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